Researchers

  • Akihiko Nakamura
  • JobAssociate Professor
    BureauGraduate school of Agriculture
    Research FieldBiophysics, Enzymology
    Research KeywordsSingle-molecule analysis, Molecular motor, polymer degrading enzyme
    Final academic historyPh.D, Graduate School of Agricultural and Life Sciences, Department of Biomaterial Sciences
  • Research History April 2013 DC2 Japan Society for the Promotion of Science
    April 2014 PD Japan Society for the Promotion of Science
    January 2015 Assistant professor Institute for Molecular Science
    Assistant professor The Graduate University for Advanced Studies
    MessageIn nature, fungi and bacteria produce celluloses and chitinases to degrade the crystalline cellulose and chitin, which are the main component of plant cell-wall and outer shell of crustacean. These enzymes continuously hydrolyze the molecular chains from the ends and move the surface of crystals. I'll apply single molecule imaging technique to investigate the moving mechanisms and try to improve the efficiency of hydrolysis by enzymes. Additionally, I'll apply the similar way of analysis to hyaluronidase and polyethylene terephtarate hydrolase. Revealing the degradation mechanism of them are important to understand the fertilization and infection of pathogen or to clean up the pieces of synthetic resins remained in environment.